Break Bad (v.) 1. To challenge convention 2. To defy authority 3. To raise hell
Chemistry: the study of change. Apply heat and, boom, no going back. Meet Walter White, high school chemistry teacher. Sleepwalking through life when, boom, a terminal diagnosis changes everything. Liberates him. Empowers him to use his chemistry skills anew: to man a rolling drug lab and finance the future for his struggling family. It's an uncontrolled experiment with the American dream. And it finally wakes him up. BREAKING BAD: Change the Equation.
The series premieres January 2008.
A more detailed description from The Futon Critic explains the premise further -- the main character has a child with cerebal palsy, and is driven to his life of crime by a cancer diagnosis.
I'm going to be blunt. This is the most jaw-droppingly dark premise for a TV series I've ever seen. There's some parallels to Weeds, but meth is a lot darker and more destructive than reefer, and the main character is in a much more hopeless situation.
Cranston is an incredibly likable actor (and the pilot appears to employ his talent for running around in his underwear), but the show is going to have to walk a tricky line to keep the audience's sympathy. Curious to see how this goes...