Let's kick it off with the obvious choice: Kevin Bacon.
Kevin Bacon was in Footloose with John Lithgow.
Mr. Lithgow was on Twenty Good Years with Jeffrey Tambor.
Mr. Tambor was on Arrested Development with Jason Bateman.
Mr. Bateman was in Dodgeball with Alan Tudyk.
Mr. Tudyk was in Knocked Up with Seth Rogen.
Mr. Rogen was on Freaks and Geeks with Jason Segel.
Now, you try it with, oh, say, Will Farrell.
Edited by The Mad Maple, Sep 15, 2007 @ 7:29 PM.